Strengthening Vaccine-Preventable Disease Prevention and Response

For programmatic or technical questions:
Randi Tolstyk
770.488.5114
ISD2025NOFO@cdc.gov

For grants management or budget questions:
Kathy Raible
770.488.2045
kdews@hrsa.gov

Grants.gov contact center:
800.518.4726
support@grants.gov
Self-service knowledge base

SAM.gov:
866.606.8220
Federal service desk

The Centers for Disease Control and Prevention (CDC) is offering funding to public health systems to protect people and communities from vaccine-preventable diseases by equitably increasing access, confidence, and demand for vaccines.

The purpose of this opportunity is to protect all people from vaccine-preventable diseases using 7 strategies designed to reduce morbidity and mortality from vaccine-preventable diseases (VPDs):

• Strengthen program infrastructure and management
• Increase vaccine access
• Improve vaccination equity
• Promote vaccine confidence and demand
• Enhance data and evaluation
• Strengthen program support for partners
• Enhance vaccination response readiness

Applicants must address and apply to all 3 program components.

Component 1: Core
The core funding formula is a weighted jurisdiction-by-jurisdiction calculation made up of the following factors:

• Base amounts
• Population
• Land area
• Uninsured adults
• Births
• Poverty
• Rural population
• Vaccines for Children (VFC) providers
• VFC eligible population

Component 2: Rapid small-scale response to VPD outbreaks or other public health emergencies
The estimated yearly funding is $250,000, as available.

Component 3: Rapid large-scale response to VPD outbreaks or other public health emergencies
The estimated yearly funding is $3,000,000, as available.

A logic model showing expected strategies, activities, and outcomes is provided in the application instructions.

Awardees will be required to ensure that all communities and populations have equitable access to vaccines, which will include recruiting and maintaining a network of public and private vaccination providers to equitably administer vaccines to eligible adult and pediatric populations. Examples of providers to enroll include:

• Primary care providers
• Federally Qualified Health Centers (FQHCs)
• Rural Health Clinics (RHCs)
• Retail pharmacies
• School-based providers

Eligible applicants include:

• The 51 state health departments or their bona fide agents, including the District of Columbia
• Local health agencies or their bona fide agents. If the city does not have a public health department, then the county covering the jurisdiction may apply
• All U.S. territories and the Freely Associated States in the Caribbean and Pacific

Expected average award per year: $6,060,606
Project period: 5 years
Estimated number of awards: 66
Estimated total program funding: $2,000,000,000

Links to the full announcement and online application process are available through grants.gov. The application instructions will be found on the related documents tab.

Applicant webinar #1
January 8, 2025
1:30 - 2:30 p.m. Eastern
Passcode: DQ#sDV!7

Applicant webinar #2
January 8, 2025
6:00 - 7:00 p.m. Eastern
Passcode: 4Vz55j$L