Rural Pharmacy and Prescription Drugs – Resources
Selected recent or important resources focusing on Rural Pharmacy and Prescription Drugs.
The 340B Drug Discount Program: Litigation Topics and Trends
Provides an overview of the 340B Drug Discount Program. Discusses litigation surrounding the 340B program, including lawsuits against 340B-covered entities over their use of contract pharmacies to distribute 340B drugs to patients and lawsuits against states that have enacted laws to protect contract pharmacies and covered entities inside their state. Describes courts' interpretation of the 340B statute. Offers considerations for the 119th Congress in light of the litigation and describes several legislative changes that Congress could make to the program if it chose to do so.
Date: 09/2025
Sponsoring organization: Congressional Research Service
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Provides an overview of the 340B Drug Discount Program. Discusses litigation surrounding the 340B program, including lawsuits against 340B-covered entities over their use of contract pharmacies to distribute 340B drugs to patients and lawsuits against states that have enacted laws to protect contract pharmacies and covered entities inside their state. Describes courts' interpretation of the 340B statute. Offers considerations for the 119th Congress in light of the litigation and describes several legislative changes that Congress could make to the program if it chose to do so.
Date: 09/2025
Sponsoring organization: Congressional Research Service
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Growth in the 340B Drug Pricing Program
Explores trends in drug purchases through the 340B program between 2010-2021. Discusses drugs purchased through the Prime Vendor Program, factors contributing to growth in the 340B program, and effects of the 340B program on the federal budget. Includes information on the growth of 340B Program participation by hospitals in Medicaid expansion and non-expansion states by Critical Access Hospital designation.
Additional links: Data Underlying Figures
Date: 09/2025
Sponsoring organization: Congressional Budget Office
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Explores trends in drug purchases through the 340B program between 2010-2021. Discusses drugs purchased through the Prime Vendor Program, factors contributing to growth in the 340B program, and effects of the 340B program on the federal budget. Includes information on the growth of 340B Program participation by hospitals in Medicaid expansion and non-expansion states by Critical Access Hospital designation.
Additional links: Data Underlying Figures
Date: 09/2025
Sponsoring organization: Congressional Budget Office
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Rural Beneficiary Access to Medicare Advantage-Part D Plans
Policy brief updating RUPRI's analysis of Medicare Advantage-Part D plans (MA-PDs) including enhanced benefit plan availability and differences in characteristics across metropolitan, micropolitan, and noncore areas. Features statistics including number of MA-PDs and stand-alone prescription drug plans (PDPs), average monthly premium costs, and availability in metropolitan, micropolitan, and noncore areas from 2008-2023.
Author(s): Edmer Lazaro, Dan M. Shane, Fred Ullrich, Keith Mueller
Date: 08/2025
Sponsoring organization: RUPRI Center for Rural Health Policy Analysis
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Policy brief updating RUPRI's analysis of Medicare Advantage-Part D plans (MA-PDs) including enhanced benefit plan availability and differences in characteristics across metropolitan, micropolitan, and noncore areas. Features statistics including number of MA-PDs and stand-alone prescription drug plans (PDPs), average monthly premium costs, and availability in metropolitan, micropolitan, and noncore areas from 2008-2023.
Author(s): Edmer Lazaro, Dan M. Shane, Fred Ullrich, Keith Mueller
Date: 08/2025
Sponsoring organization: RUPRI Center for Rural Health Policy Analysis
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Congress Must Act to Bring Needed Reforms to the 340B Drug Pricing Program: Majority Staff Report
Presents findings from a U.S. Senate Committee on Health, Education, Labor & Pensions majority staff report on how covered entities generate and use revenue from the 340B Drug Pricing Program and how patients benefit from the program. Describes data and information collected from hospital covered entities, Bon Secours Mercy Health and Cleveland Clinic; Federally Qualified Health Center (FQHC) covered entities, Sun River Health and Yakima Valley Farm Workers Clinic; contract pharmacies, CVS Health and Walgreens; and drug manufacturers, Eli Lilly and Amgen. Includes rural references throughout.
Date: 04/2025
Sponsoring organization: Senate Committee on Health, Education, Labor & Pensions
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Presents findings from a U.S. Senate Committee on Health, Education, Labor & Pensions majority staff report on how covered entities generate and use revenue from the 340B Drug Pricing Program and how patients benefit from the program. Describes data and information collected from hospital covered entities, Bon Secours Mercy Health and Cleveland Clinic; Federally Qualified Health Center (FQHC) covered entities, Sun River Health and Yakima Valley Farm Workers Clinic; contract pharmacies, CVS Health and Walgreens; and drug manufacturers, Eli Lilly and Amgen. Includes rural references throughout.
Date: 04/2025
Sponsoring organization: Senate Committee on Health, Education, Labor & Pensions
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Screening and Referral Programs for Diabetes and Cardiovascular Disease: Can Community Pharmacists Bridge the Care Gap?
Examines the community-based valued-driven care initiative (CVCI) in community pharmacies to evaluate its effectiveness related to screening and referral (S&R) to treat cardiovascular disease (CVD) and diabetes mellitus (DM). Analyzes patient demographics and success rates of CVD and DM S&R in 6 community pharmacies, with both rural and urban locations represented.
Author(s): Melanie Livet, Amber Watson, Shweta Pathak, et al.
Citation: Exploratory Research in Clinical and Social Pharmacy, 17, 100539
Date: 03/2025
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Examines the community-based valued-driven care initiative (CVCI) in community pharmacies to evaluate its effectiveness related to screening and referral (S&R) to treat cardiovascular disease (CVD) and diabetes mellitus (DM). Analyzes patient demographics and success rates of CVD and DM S&R in 6 community pharmacies, with both rural and urban locations represented.
Author(s): Melanie Livet, Amber Watson, Shweta Pathak, et al.
Citation: Exploratory Research in Clinical and Social Pharmacy, 17, 100539
Date: 03/2025
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Opioid Use Among Rural Medicare Beneficiaries
Examines trends in prescription opioid use among Medicare beneficiaries in rural areas, utilizing 2010-2017 Medicare Current Beneficiary Survey (MCBS) data. Provides data on receipt of opioid prescriptions among community-dwelling and facility-dwelling beneficiaries, associations between prescribing and chronic overlapping pain conditions (COPCs), and prescriptions exceeding CDC guidelines. Includes rural-urban comparisons.
Author(s): Yvonne Jonk, Heidi O'Connor, Karen Pearson, et al.
Date: 01/2025
Sponsoring organization: Maine Rural Health Research Center
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Examines trends in prescription opioid use among Medicare beneficiaries in rural areas, utilizing 2010-2017 Medicare Current Beneficiary Survey (MCBS) data. Provides data on receipt of opioid prescriptions among community-dwelling and facility-dwelling beneficiaries, associations between prescribing and chronic overlapping pain conditions (COPCs), and prescriptions exceeding CDC guidelines. Includes rural-urban comparisons.
Author(s): Yvonne Jonk, Heidi O'Connor, Karen Pearson, et al.
Date: 01/2025
Sponsoring organization: Maine Rural Health Research Center
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Projecting the Impact of the $2,000 Part D Out-Of-Pocket Cap for Medicare Part D Enrollees with High Prescription Drug Spending
Examines the impact of the Medicare Part D $2,000 cap on out-of-pocket prescription drugs. Provides projected savings according to low-income subsidy (LIS) status, state, and demographic characteristics, including urban, rural-micropolitan, rural-other, or unclassified geographic location.
Date: 01/2025
Sponsoring organization: HHS Office of the Assistant Secretary for Planning and Evaluation
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Examines the impact of the Medicare Part D $2,000 cap on out-of-pocket prescription drugs. Provides projected savings according to low-income subsidy (LIS) status, state, and demographic characteristics, including urban, rural-micropolitan, rural-other, or unclassified geographic location.
Date: 01/2025
Sponsoring organization: HHS Office of the Assistant Secretary for Planning and Evaluation
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Buprenorphine Injection Among Rural Persons Who Inject Drugs
Describes buprenorphine use by rural people who inject drugs, using data from the Rural Opioid Initiative, to inform patient-clinician discussions and public health interventions. Features demographics and behavioral characteristics of 2,369 people who were surveyed between 2018-2020.
Author(s): Kaitlin A. Zinsli, Elenore P. Bhatraju, Judith Feinberg, et al.
Citation: JAMA Network Open, 7(12), e2450108
Date: 12/2024
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Describes buprenorphine use by rural people who inject drugs, using data from the Rural Opioid Initiative, to inform patient-clinician discussions and public health interventions. Features demographics and behavioral characteristics of 2,369 people who were surveyed between 2018-2020.
Author(s): Kaitlin A. Zinsli, Elenore P. Bhatraju, Judith Feinberg, et al.
Citation: JAMA Network Open, 7(12), e2450108
Date: 12/2024
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Pharmacy-Based Preventive Services for Opioid Use Disorder: A Survey of U.S. Pharmacists
Examines pharmacist perceptions related to addressing opioid use disorder (OUD) and substance use disorder (SUD) in their patients. Utilizes online survey data from 1,146 pharmacists to analyze pharmacist concerns about drug use; drug screenings, interventions, and referrals; and commitment and readiness to address OUD and SUD in their patients. Includes breakdowns of pharmacist demographics as well as rurality of pharmacy locations.
Author(s): Li-Tzy Wu, Jacquie King, Kathryn Hefner, et al.
Citation: Addiction Science & Clinical Practice, 19, 88
Date: 12/2024
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Examines pharmacist perceptions related to addressing opioid use disorder (OUD) and substance use disorder (SUD) in their patients. Utilizes online survey data from 1,146 pharmacists to analyze pharmacist concerns about drug use; drug screenings, interventions, and referrals; and commitment and readiness to address OUD and SUD in their patients. Includes breakdowns of pharmacist demographics as well as rurality of pharmacy locations.
Author(s): Li-Tzy Wu, Jacquie King, Kathryn Hefner, et al.
Citation: Addiction Science & Clinical Practice, 19, 88
Date: 12/2024
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Community Responses and Adaptations Following the Closure of a Rural Pharmacy and Primary Care Facility
Uses interviews with 26 community members to identify the impact of a pharmacy and primary healthcare facility closure in a rural Pennsylvania community. Discusses challenges for vulnerable populations, distance to care, social networks, delayed treatment, emergency medical services, alternative medicine, and more.
Author(s): Hazel Velasco Palacios, Kristina Brant, Danielle Rhubart, Jorden Jackson
Citation: Journal of Rural Health 41(2), e12896
Date: 11/2024
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Uses interviews with 26 community members to identify the impact of a pharmacy and primary healthcare facility closure in a rural Pennsylvania community. Discusses challenges for vulnerable populations, distance to care, social networks, delayed treatment, emergency medical services, alternative medicine, and more.
Author(s): Hazel Velasco Palacios, Kristina Brant, Danielle Rhubart, Jorden Jackson
Citation: Journal of Rural Health 41(2), e12896
Date: 11/2024
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Last Updated: 9/10/2025