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Rural Health
Resources by Topic: Substance use and misuse

Can a Participant-Referred "Study Buddy" Increase Retention of Rural People Who Use Drugs in Research? A Multi-Site, Randomized Trial
Presents a study exploring the efficacy of an intervention aiming to increase retention of rural people who use drugs (PWUD) participating in randomized trials. Highlights an intervention involving participant recruitment of a support person, or "study buddy", to aid in the their continued participation in the study. Compares the efficacy of this intervention with standard retention practices.
Author(s): April M. Young, Kathryn E. Lancaster, Miriam R. Elman, et al.
Citation: Addiction, 121(4), 894-907
Date: 04/2026
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Resilience to Stigma in Medical, Social, and Employment Contexts among People Who Inject Drugs in Rural Ohio: Adapting the 10-Item Connor-Davidson Resilience Scale
Explores the role stigma related to drug use and HIV plays in the lives of people who inject drugs (PWID) and aims to build resilience in medical, social, and employment contexts for PWID in rural Appalachian Ohio. Presents results from a series of interviews and a qualitative survey placing participants on the Connor-Davidson Resilience Scale.
Author(s): Madison N. Enderle, Rebecca H. Neiberg, Stacy M. Endres-Dighe, et al.
Citation: AIDS and Behavior, 30, 894-906
Date: 03/2026
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Comparing the Care and Distance Traveled by Rural and Urban Medicaid Beneficiaries With Opioid Use Disorder
Results of a study describing the treatment for rural and urban Medicaid beneficiaries with opioid use disorder in 2019. Features demographics and statistics on number of visits and travel time and distance, with breakdowns by 5 levels of population density.
Author(s): C. Holly A. Andrilla, Sara C. Woolcock, Lisa A. Garberson, Janessa M. Graves
Date: 03/2026
Sponsoring organization: WWAMI Rural Health Research Center
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State of North Carolina's Mental Health and Substance Use Services Workforce: Need, Supply, and Distribution Landscape Assessment
Provides an overview on need, supply, and distribution of behavioral health professionals in North Carolina. Includes county-level maps and data on workforce and behavioral health issues.
Author(s): Brianna Lombardi, Jennifer Headley, Monica P. Jimenez, et al.
Date: 03/2026
Sponsoring organization: The Cecil G. Sheps Center for Health Services Research
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Empowering Rural Communities: Overcoming Barriers to Substance Use Treatment
Webinar recording discusses the ways rural communities can overcome barriers to substance use disorder (SUD) treatment and uptake. Explores substance use data for rural communities and outlines common barriers, such as travel times and distance to care, provider shortages, and concerns about stigma and patient confidentiality. Highlights strategies for rural communities to leverage their community bonds and faith communities to address SUD, and details models for expanding treatment and patient support in rural areas.
Additional links: Webinar Slides
Date: 02/2026
Sponsoring organization: Addiction Technology Transfer Center Network
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Methamphetamine Use, Mental Health Comorbidities, and Treatment in Rural and Urban Areas, 2016-2019
Examines the prevalence of methamphetamine use by level of rurality and U.S. region, with data on methamphetamine use and mental illness, suicide and suicidal ideation, concurrent alcohol use, treatment for methamphetamine use disorder, method of use, and other relating to methamphetamine use prevalence and associated risks.
Author(s): Signe E. Burchim, Lisa A. Garberson, Sara C. Woolcock, et al.
Date: 02/2026
Sponsoring organization: WWAMI Rural Health Research Center
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The Economic Burden of Mental Health and Substance Use Disorders: The United States and the Heartland Region
Examines how mental health and substance use disorders (MH/SUDs) affect healthcare spending and lost productivity in the heartland region of the United States, using 2016-2023 AHRQ MEPS data from seven selected states. See page 20 for discussion of rurality as a factor influencing MH/SUD treatment access.
Author(s): Alexandra F. Kritikos, Meg Hefferon, Devi Chelluri, MacKenzie L. Hughes
Date: 02/2026
Sponsoring organization: NORC at the University of Chicago
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Clinical and Demographic Characteristics of Participants in a Hepatitis C Treatment Trial in Rural Kentucky: How Policies Around Treatment Access May Impact Elimination Efforts in the United States
Examines characteristics and drug use patterns of the participants in the Kentucky Viral Hepatitis C Treatment (KeY Treat) trial, which focuses on improving access to direct acting antiviral (DAA) drugs to treat the hepatitis C virus (HCV). Discuses Medicaid policy related to DAA treatment of HCV in a rural, Appalachian community in Kentucky.
Author(s): Jennifer R. Havens, Brittney D. Williams, Takako Schaninger, et al.
Citation: Journal of Rural Health, 42(1), e70128
Date: 02/2026
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The Interaction of Tobacco Retailer Density and Rurality with Tobacco Use Prevalence in Kentucky
Explores the relationship between the prevalence of tobacco retailers and rates of tobacco use in rural counties in Kentucky. Highlights rates of smoking and smokeless tobacco use by county retailer density.
Author(s): Shyanika W. Rose, W. Jay Christian, Judy van de Venne, et al.
Citation: Journal of Rural Health, 42(1), e70106
Date: 01/2026
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Expanding Access to Harm Reduction in Rural Communities Through Community-Informed Public Health Vending Machines
Examines the role of public health vending machines (PHVMs) to address the opioid epidemic in rural counties in North Carolina. Utilizes a community-based participatory research (CBPR) approach to gather qualitative feedback among people with substance use experience regarding issues such as naloxone access, stigma, preferred PHVM locations and distribution models, and more.
Author(s): Lori Ann Eldridge, Christian Dotson, Lauren Harrell, et al.
Citation: Harm Reduction Journal, 23, 26
Date: 01/2026
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