Rural Health
Resources by Topic: Substance use and misuse
The Economic Burden of Mental Health and Substance Use Disorders: The United States and the Heartland Region
Examines how mental health and substance use disorders (MH/SUDs) affect healthcare spending and lost productivity in the heartland region of the United States, using 2016-2023 AHRQ MEPS data from seven selected states. See page 20 for discussion of rurality as a factor influencing MH/SUD treatment access.
Author(s): Alexandra F. Kritikos, Meg Hefferon, Devi Chelluri, MacKenzie L. Hughes
Date: 02/2026
Sponsoring organization: NORC at the University of Chicago
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Examines how mental health and substance use disorders (MH/SUDs) affect healthcare spending and lost productivity in the heartland region of the United States, using 2016-2023 AHRQ MEPS data from seven selected states. See page 20 for discussion of rurality as a factor influencing MH/SUD treatment access.
Author(s): Alexandra F. Kritikos, Meg Hefferon, Devi Chelluri, MacKenzie L. Hughes
Date: 02/2026
Sponsoring organization: NORC at the University of Chicago
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Clinical and Demographic Characteristics of Participants in a Hepatitis C Treatment Trial in Rural Kentucky: How Policies Around Treatment Access May Impact Elimination Efforts in the United States
Examines characteristics and drug use patterns of the participants in the Kentucky Viral Hepatitis C Treatment (KeY Treat) trial, which focuses on improving access to direct acting antiviral (DAA) drugs to treat the hepatitis C virus (HCV). Discuses Medicaid policy related to DAA treatment of HCV in a rural, Appalachian community in Kentucky.
Author(s): Jennifer R. Havens, Brittney D. Williams, Takako Schaninger, et al.
Citation: Journal of Rural Health, 42(1), e70128
Date: 02/2026
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Examines characteristics and drug use patterns of the participants in the Kentucky Viral Hepatitis C Treatment (KeY Treat) trial, which focuses on improving access to direct acting antiviral (DAA) drugs to treat the hepatitis C virus (HCV). Discuses Medicaid policy related to DAA treatment of HCV in a rural, Appalachian community in Kentucky.
Author(s): Jennifer R. Havens, Brittney D. Williams, Takako Schaninger, et al.
Citation: Journal of Rural Health, 42(1), e70128
Date: 02/2026
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Expanding Access to Harm Reduction in Rural Communities Through Community-Informed Public Health Vending Machines
Examines the role of public health vending machines (PHVMs) to address the opioid epidemic in rural counties in North Carolina. Utilizes a community-based participatory research (CBPR) approach to gather qualitative feedback among people with substance use experience regarding issues such as naloxone access, stigma, preferred PHVM locations and distribution models, and more.
Author(s): Lori Ann Eldridge, Christian Dotson, Lauren Harrell, et al.
Citation: Harm Reduction Journal, 23, 26
Date: 01/2026
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Examines the role of public health vending machines (PHVMs) to address the opioid epidemic in rural counties in North Carolina. Utilizes a community-based participatory research (CBPR) approach to gather qualitative feedback among people with substance use experience regarding issues such as naloxone access, stigma, preferred PHVM locations and distribution models, and more.
Author(s): Lori Ann Eldridge, Christian Dotson, Lauren Harrell, et al.
Citation: Harm Reduction Journal, 23, 26
Date: 01/2026
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Integrating Substance Use Disorder Prevention with Physical Health Care: Progress in States
Discusses how states can integrate substance use disorder (SUD) prevention with physical healthcare, including examples of integration activities that are applicable to rural settings. Highlights opportunities for behavioral health integration aimed at serving adolescents aged 12-18. Includes a rural case study example of a school-based health center SUD prevention program in Oregon.
Date: 01/2026
Sponsoring organization: Substance Abuse and Mental Health Services Administration
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Discusses how states can integrate substance use disorder (SUD) prevention with physical healthcare, including examples of integration activities that are applicable to rural settings. Highlights opportunities for behavioral health integration aimed at serving adolescents aged 12-18. Includes a rural case study example of a school-based health center SUD prevention program in Oregon.
Date: 01/2026
Sponsoring organization: Substance Abuse and Mental Health Services Administration
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Mobile Telemedicine for Treating Chronic Hepatitis C among Rural People Who Inject Drugs: A Randomized Clinical Trial
Explores the efficacy of a mobile telemedicine-based intervention for hepatitis C (HCV) infections among rural people who inject drugs. Highlights the outcomes of the intervention in terms of treatment initiation, viral clearance, and reduced equipment sharing. Breaks down data by demographic characteristics, outcomes, and risks and probabilities, among other measures.
Author(s): Peter D. Friedmann, Donna Wilson, David de Gijsel, et al.
Citation: JAMA Network Open, 9(1), e2555125
Date: 01/2026
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Explores the efficacy of a mobile telemedicine-based intervention for hepatitis C (HCV) infections among rural people who inject drugs. Highlights the outcomes of the intervention in terms of treatment initiation, viral clearance, and reduced equipment sharing. Breaks down data by demographic characteristics, outcomes, and risks and probabilities, among other measures.
Author(s): Peter D. Friedmann, Donna Wilson, David de Gijsel, et al.
Citation: JAMA Network Open, 9(1), e2555125
Date: 01/2026
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Examining Rural Community Pharmacists' Knowledge and Practices in Opioid Overdose Prevention and Treatment Services in the Southeastern United States
Highlights a study on the knowledge and practices of rural pharmacists around opioid use disorder-related education and counseling in the Southeastern U.S. Presents data by pharmacist demographic characteristics, knowledge, and experience with medications for opioid use disorder (MOUD).
Author(s): Stefanie P. Ferreri, Paige Q. Ngo, Kaileigh D. Yen, Kevin Wang, et al.
Citation: Harm Reduction Journal, 23(11)
Date: 01/2026
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Highlights a study on the knowledge and practices of rural pharmacists around opioid use disorder-related education and counseling in the Southeastern U.S. Presents data by pharmacist demographic characteristics, knowledge, and experience with medications for opioid use disorder (MOUD).
Author(s): Stefanie P. Ferreri, Paige Q. Ngo, Kaileigh D. Yen, Kevin Wang, et al.
Citation: Harm Reduction Journal, 23(11)
Date: 01/2026
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"It's a Last Straw Situation"; Overdose Response and Preferences for Seeking Support from Emergency Services During Overdose in Rural Ohio
Explores the perceptions and preferences of people in rural Ohio affected by the opioid epidemic about contacting first responders during an overdose. Bases findings on a survey of 43 rural people who have experienced or witnessed an overdose on the factors they considered when deciding whether or not to call 911.
Author(s): David C. Colston, Vivian F. Go, Clare Barrington, et al.
Citation: PLOS One, 21(1), e0338689
Date: 01/2026
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Explores the perceptions and preferences of people in rural Ohio affected by the opioid epidemic about contacting first responders during an overdose. Bases findings on a survey of 43 rural people who have experienced or witnessed an overdose on the factors they considered when deciding whether or not to call 911.
Author(s): David C. Colston, Vivian F. Go, Clare Barrington, et al.
Citation: PLOS One, 21(1), e0338689
Date: 01/2026
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Supporting Rural Primary Care Practices in Delivering Care for Chronic Pain
Provides guidance on chronic pain care in rural primary care practices. Discusses best practices for delivering high-quality care in rural areas, including discussion of substance use disorder treatment and prevention, barriers to care delivery in rural practices, and more.
Date: 01/2026
Sponsoring organization: University of Rochester Medicine Recovery Center of Excellence
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Provides guidance on chronic pain care in rural primary care practices. Discusses best practices for delivering high-quality care in rural areas, including discussion of substance use disorder treatment and prevention, barriers to care delivery in rural practices, and more.
Date: 01/2026
Sponsoring organization: University of Rochester Medicine Recovery Center of Excellence
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Exploring the Use of Telemedicine to Expand Addiction and Recovery Resources in Great Plains Tribal Communities
Explores the use of telemedicine to provide medications for opioid use disorder (MOUD) to patients in tribal communities. Explores the barriers and facilitators to implementing telemedicine-based MOUD services across the Great Plains Area of the Indian Health Service.
Author(s): Michael C. Harding, Anna C. Kihlstrom, Allison Kelliher, et al.
Citation: Journal of Rural Health, 42(1), e70113
Date: 01/2026
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Explores the use of telemedicine to provide medications for opioid use disorder (MOUD) to patients in tribal communities. Explores the barriers and facilitators to implementing telemedicine-based MOUD services across the Great Plains Area of the Indian Health Service.
Author(s): Michael C. Harding, Anna C. Kihlstrom, Allison Kelliher, et al.
Citation: Journal of Rural Health, 42(1), e70113
Date: 01/2026
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America's Health Rankings Annual Report 2025
Provides a national and state-by-state overview of population health by analyzing 99 measures drawn from 31 data sources to describe and rank health outcomes in the U.S. Analyzes and presents data on disparities by geography and demographic characteristics throughout. See the section titled, "Spotlight: Rural Communities," for information on trends in colorectal and breast cancer screening rates and physical inactivity of adults in rural areas between 2022 and 2024.
Additional links: Executive Brief
Date: 01/2026
Sponsoring organization: United Health Foundation
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Provides a national and state-by-state overview of population health by analyzing 99 measures drawn from 31 data sources to describe and rank health outcomes in the U.S. Analyzes and presents data on disparities by geography and demographic characteristics throughout. See the section titled, "Spotlight: Rural Communities," for information on trends in colorectal and breast cancer screening rates and physical inactivity of adults in rural areas between 2022 and 2024.
Additional links: Executive Brief
Date: 01/2026
Sponsoring organization: United Health Foundation
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