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Rural Health
Resources by Topic: Cardiovascular disease

Uranium Exposure, Hypertension, and Blood Pressure in the Strong Heart Family Study
Examines the correlation between uranium exposure and health conditions such as hypertension and blood pressure changes in rural, tribal communities. Analyzes health status and uranium levels of 1,453 participants in the Strong Heart Family Study. Discusses rock and soil health, groundwater, and surface water contamination as factors in uranium exposure.
Author(s): Kevin P. Patterson, Abigail Onderwyzer Gold, Miranda J. Spratlen, et al.
Citation: Preventing Chronic Disease, 22
Date: 04/2025
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Initiating Research in Indian Country: Lessons From the Strong Heart Study
Discusses the process of the National Heart, Lung, and Blood Institute (NHLBI) initiating studies to examine cardiovascular disease in rural and remote areas, isolated populations, and sovereign nations. Discusses the steps in conducting research with a focus on building trust, transparent implementation, and mutual feedback and results sharing.
Author(s): Barbara V. Howard, Elisa T. Lee, Thomas K. Welty, Richard R. Fabsitz
Citation: Preventing Chronic Disease, 22
Date: 04/2025
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Are HHC Scores a Reliable Health Status Indicator Across Rural and Urban Areas?
Examines differences in Centers for Medicare & Medicaid Services Hierarchical Condition Category (HCC) risk scores between rural and urban Medicare Fee-for-Service (FFS) beneficiaries and analyzes which factors drive observed differences. Features statistics with breakdowns by urban, large rural, small rural, and isolated rural areas for 4 chronic conditions in 2019-2020.
Author(s): Craig D. Holden, Alana Knudson, Marilyn Klug, Samantha Augenbraun, Shena Popat
Date: 04/2025
Sponsoring organization: ETSU/NORC Rural Health Research Center
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Vitamin D Deficiency and Cardiovascular Disease Risk Factors Among American Indian Adolescents: The Strong Heart Family Study
Examines Vitamin D deficiency in adolescents from 12 tribal communities and the correlation with cardiovascular disease (CVD) risk factors. Utilizes data from sovereign tribal nations located in multiple U.S. states and provides breakdowns on adolescents' demographic profiles, health status, and Vitamin D deficiency status.
Author(s): Jessica A. Reese, Erin Davis, Amanda M. Fretts, et al.
Citation: Preventing Chronic Disease, 22
Date: 04/2025
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Study Protocol of Sustaining Home Palliative Care for Patients with Heart Failure (Hf) and Their Family Caregivers in Rural Appalachia: A Mixed Methods Randomized Clinical Trial
Study protocol to examine an integrated nurse-led intervention bundle for patients with heart failure and their family caregivers regarding home supportive end-of-live palliative care in rural West Virginia. Discusses the assessment of the intervention's sustainability with rural stakeholders, visiting volunteers, and the West Virginia Faith Community Nurse Network.
Author(s): Ubolrat Piamjariyakul, Stephanie Young, Angel Smothers, et al.
Citation: BMC Palliative Care, 24(1)
Date: 03/2025
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Two Modeling Strategies in Analyzing Clustered Time-to-Event Data: The Strong Heart Family Study
Examines the use of the shared frailty and marginal Cox proportional hazards models to study associations between leukocyte telomere length and time-to-incident stroke among 4,635 American Indian study participants from tribal communities in Arizona, Oklahoma, North Dakota, and South Dakota. Discusses effective use of data models for population genetic studies.
Author(s): Heather Willmott, Caroline Gochanour, Kai Ding, et al.
Citation: Preventing Chronic Disease, 22, 240387
Date: 03/2025
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Disparities in Cardiovascular Disease Prevalence by Race and Ethnicity, Socioeconomic Status, Urbanicity, and Social Determinants of Health Among Medicare Beneficiaries With Diabetes
Examines demographic disparities in cardiovascular disease prevalence among people with diabetes, utilizing 2015–2019 Medicare Current Beneficiary Survey data. Includes sociodemographic data, including rural-urban comparisons, on crude and adjusted prevalence of myocardial infarction, stroke, and heart failure.
Author(s): Xilin Zhou, Joohyun Park, Deborah B. Rolka, et al.
Citation: Preventing Chronic Disease, 22, 240270
Date: 03/2025
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Screening and Referral Programs for Diabetes and Cardiovascular Disease: Can Community Pharmacists Bridge the Care Gap?
Examines the community-based valued-driven care initiative (CVCI) in community pharmacies to evaluate its effectiveness related to screening and referral (S&R) to treat cardiovascular disease (CVD) and diabetes mellitus (DM). Analyzes patient demographics and success rates of CVD and DM S&R in 6 community pharmacies, with both rural and urban locations represented.
Author(s): Melanie Livet, Amber Watson, Shweta Pathak, et al.
Citation: Exploratory Research in Clinical and Social Pharmacy, 17, 100539
Date: 03/2025
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Are There Rural–Urban Disparities in Cardiovascular Disease Hospitalization and Other Outcomes in People with Gout? A Nationwide U.S. Study
Examines associations between rural or urban dwelling and myocardial infarction hospitalization among people with gout, using 2016-2019 U.S. National Inpatient Sample data.
Author(s): Jasvinder A. Singh, Sumanth R. Chandrupatla
Citation: Rheumatology, 64(8), 4744-4749
Date: 02/2025
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2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association
Compiles national data on heart disease, stroke, and health behaviors and other factors affecting cardiovascular health. Mentions demographic health disparities throughout, including rural-urban health disparities.
Author(s): Seth S. Martin, Aaron W. Aday, Norrina B. Allen, et al.
Citation: Circulation, 151:e1-e620
Date: 01/2025
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