Telephone-Based Guideline-Directed Medical Therapy Optimization in Navajo Nation: The Hózhó Randomized Clinical Trial

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Explores whether a guideline-directed medical therapy (GDMT) is initiated and titrated through telehealth improves GDMT use among patients with heart failure with reduced ejection fraction in Navajo Nation. Summarizes results of a stepped-wedge, pragmatic comparative effectiveness trial conducted from February to August 2023 at two Indian Health Service facilities in rural Navajo Nation. Discusses the importance of community-designed and locally-tailored strategies to improve GDMT rates.

Lauren A. Eberly, Ada Tennison, Daniel Mays, et al.

JAMA Internal Medicine, 184(6), 681-690

04/2024

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Access · American Indian or Alaska Native · Cardiovascular disease · Pharmacy and prescription drugs · Statistics and data · Telehealth