Associations Between COVID-19 Therapies and Outcomes in Rural and Urban America: A Multisite, Temporal Analysis from the Alpha to Omicron SARS-CoV-2 Variants

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Examines COVID-19 treatment, health outcomes, and mortality disparities in rural and urban areas of the United States. Analyzes 2021-2023 National COVID Cohort Collaborative (N3C) data from 3,018,646 patients to break down COVID-19 disparities according to patient demographics, vaccine status, comorbidities, U.S. Census region, and adverse inpatient events, as well as urban, urban-adjacent, or nonurban-adjacent location.

A. Jerrod Anzalone, William H. Beasley, Kimberly Murray, et al.

Journal of Rural Health, 41(1), e12857

2025

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COVID-19 · Health conditions · Health disparities · Mortality · Rural-urban differences · Specialty care · Statistics and data · Vaccination